Cerebrospinal fluid (CSF) cell count with differential is done to analyze the cellular components, number, and types of cells distributed in the CSF to obtain diagnostic information about various neurological conditions such as meningitis, encephalitis, and tumors. The total number of CSF cells counted on the stained slide is studied. An elevated count with differential cells gives insight into the type of infection.

References:

• Fulkerson DH, Sivaganesan A, Hill JD, Edwards JR, Shoja MM, Boaz JC, Jea A. Progression of cerebrospinal fluid cell count and differential over a treatment course of shunt infection. J Neurosurg Pediatr. 2011 December;8(6):613-9. doi: 10.3171/2011.8.PEDS11236. Accessed on Jan 31st,2024.
• Seehusen DA, Reeves MM, Fomin DA. Cerebrospinal fluid analysis. Am Fam Physician. 2003 Sep 15;68(6):1103-8. Accessed on Jan 31st,2024.
• Data on File: PureLab DOS V5, November 10th, 2023.