Fibrinogen is a key protein converted to fibrin during the final stages of the coagulation cascade. A fibrinogen assay is indicated to assess the adequacy of fibrinogen in the blood and helps to monitor suspected clotting disorders, liver disease, disseminated intravascular coagulation, inflammation, or certain cancers, or monitoring during certain therapies as abnormal fibrinogen levels induce a risk of bleeding.

References:

• Ogawa S, Tanaka KA, Nakajima Y, Nakayama Y, Takeshita J, Arai M, Mizobe T. Fibrinogen measurements in plasma and whole blood: a performance evaluation study of the dry-hematology system. Anesth Analg. 2015 January;120(1):18-25. doi: 10.1213/ANE.0000000000000448. Accessed on Jan 31st,2024.
• Miesbach W, Schenk J, Alesci S, Lindhoff-Last E. Comparison of the fibrinogen Clauss assay and the fibrinogen PT derived method in patients with dysfibrinogenemia. Thromb Res. 2010 December;126(6):e428-33. doi: 10.1016/j.thromres.2010.09.004.Accessed on Jan 31st,2024.
• Data on File: PureLab DOS V5, November 10^th, 2023.