Platelets play a crucial role in hemostasis by adhering to the site of injury and undergoing aggregation to form a stable primary hemostatic plug. Platelet function screening tests assess the ability of platelets to form a primary plug through a series of whole-blood impedance aggregometry and platelet function analyzers combining bleeding time, platelet count, and receptor inhibition studies to provide insights on platelet function disorders.
References:
- Szanto T, Zetterberg E, Ramström S, Leinøe EB, Holme PA, Antovic JP, Holmström M, Onundarson PT, Pikta M, Vaide I, Olsson A, Magnusson M, Kärkkäinen S, Bitar M, Poulsen LH, Lassila R; Nordic Haemophilia Council. Platelet function testing: Current practice among clinical centres in Northern Europe. Haemophilia. 2022 July;28(4):642-648. doi: 10.1111/hae.14578. Accessed on Jan 31st,2024.
- Moenen FCJI, Vries MJA, Nelemans PJ, van Rooy KJM, Vranken JRRA, Verhezen PWM, Wetzels RJH, Ten Cate H, Schouten HC, Beckers EAM, Henskens YMC. Screening for platelet function disorders with Multiplate and platelet function analyzer. Platelets. 2019;30(1):81-87. doi: 10.1080/09537104.2017.1371290.Accessed on Jan 31st,2024.
- Data on File: PureLab DOS V5, November 10th, 2023.
