Ascorbate oxidase, an enzyme involved in the oxidation of ascorbic acid (vitamin C), may trigger type 1 allergic reactions in some individuals who produce IgE antibodies. It may present with allergic GI manifestations, dermatitis, atopy with itching, swelling, or severe anaphylaxis in a few cases. Healthcare providers utilize this test to determine allergic status and guide allergen-specific immunotherapy.

Important note: Minimum volume is 1 mL and 0.5 mL for every additional allergen.