Cat dander epithelium produces allergens such as lipocalins (Fel-d-4) and uteroglobins (Fel-d-1) that are often spread in the air as tiny particles, causing sensitization in humans to elicit type 1 hypersensitivity reactions, producing IgE antibodies. These antibodies cause allergic reactions, predominantly bronchial asthma, rhinitis, conjunctivitis, gastrointestinal symptoms, atopy, or occasionally anaphylaxis. IgE levels help healthcare professionals with diagnosis, planning immunotherapy, and cat exposure prevention.

Important note: Minimum volume is 1 mL and 0.5 mL for every additional allergen.