Cheese-ripening rooms provide an exceptional environment for the growth of several undesirable molds. It can induce food or inhalant allergens, leading to Type 1 IgE hypersensitivity, which manifests as gastric and respiratory as well as cutaneous allergic conditions including allergic rhinitis, asthma, anaphylaxis, and atopic dermatitis. IgE estimation helps healthcare professionals with diagnosis, immunotherapy, and exposure prevention.