The IgH Gene is a unique immunoglobulin receptor gene showing an unusual genetic rearrangement of the IgH gene. Hematological malignancies, such as B-cell lymphomas, show uncontrolled proliferation of B Cells, leading to the expansion of the population of cells with identical IgH gene rearrangements. IgH Gene Clonality PCR detects the clonality of immunoglobulin heavy chain (IgH) genes, helping healthcare professionals diagnose and monitor neoplasms.