Plasminogen is a glycoprotein formed in the liver and circulates in the blood. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products. Plasminogen assay is employed by healthcare professionals for Pseudomembranous disease (e.g., ligneous conjunctivitis) as well as Idiopathic thromboembolic disease (if other causes of thrombophilia are eliminated).