The Serum 21-Deoxycortisol test is conducted to measure the levels of the steroid 21-Deoxycortisol. Serum 21-deoxycortisol (21DF) is an adrenal-specific derivative of 11β-hydroxylase from 17OHP and serves as a sensitive and specific biomarker for 21-hydroxylase deficiency (21-OHP). This test helps healthcare professionals to identify congenital adrenal hyperplasia and high-risk newborns for 21OHD in the general population.