Aldosterone is a mineralocorticoid and steroid hormone synthesized by the adrenal gland, and its secretion is controlled by the renin-angiotensin-aldosterone system, plasma potassium concentration, and blood pressure.  By measuring the levels of serum aldosterone (supine), healthcare professionals can diagnose primary and secondary aldosteronism, adrenal hyperplasia, and hypoaldosteronism, facilitating prompt and effective intervention.