The Hepatitis B e Antibody test detects anti-HBe antibodies against antigens of hepatitis B virus detectable 8 to 16 weeks post-infection. Determining the presence or absence of detectable hepatitis B e antibody in monitoring infection status of individuals with chronic hepatitis B. Determining infectivity of hepatitis B virus (HBV) carriers Anti-HBe usually remains detectable for several years after recovery from acute infection. In hepatitis B virus (HBV) carriers and in patients with chronic hepatitis B, positive anti-HBe results usually indicate inactivity of the virus and low infectivity of the patients. Positive anti-HBe results in the presence of detectable HBV DNA in serum indicate active viral replication.