Chaetomium globosum is a saprophytic ascomycete fungus and hydrophilic mold found in soil, plant debris, and water-damaged buildings. It is known for mycotoxin production and allergens causing Type 1 IgE hypersensitivity in respiratory and cutaneous allergic conditions such as allergic rhinitis, asthma, hypersensitivity pneumonia, and atopic dermatitis. IgE estimation helps healthcare professionals with diagnosis and exposure prevention among workers in damp buildings.