Immunofluorescent Study – Each Antibody
In an immunofluorescent study, each antibody detects a specific tissue cellular antigen using targeted antibodies tagged with fluorescent markers and visualized with a fluorescent microscope. This test is indicated for diagnosing immunological disorders affecting the kidney, blood vessels, and neurological systems. It provides higher-resolution molecular insights at the microscopic level, enhancing diagnostic precision and facilitating […]
In Situ Hybridization of Epstein-Barr Virus (ISH EBV) DNA
In situ hybridization (ISH) is a method by which specific nucleotide sequences are recognized in tissue sections. Its application has been predominantly in viral infections, such as the detection of Epstein-Barr virus by the presence of small nuclear RNAs (EBERs). This test aids healthcare providers in accurately diagnosing EBV-associated lymphoma and infectious mononucleosis.
Immunohistochemistry (IHC) Staining Request: Each Antibody
An immunohistochemistry (IHC) staining request for each antibody is requested to obtain the in-depth and precise nature of cellular morphology and function. The test involves staining tissue sections with IHC markers, developing antigen-antibody binding, a detection system, and microscopy to facilitate protein visualization with specific antibodies. IHC adds value to characterizing the nature of tumors, […]
Intraoperative Consultation (IOC) of Cytological Preparations, i.e., Touch Preparation
This test is requested for rapid interpretation of cytology slides to facilitate perioperative tissue diagnosis. Resected tissue margin surfaces imprinted on glass slides are subjected to rapid staining and quick microscopic examination. Touch-preparation cytology slides provide real-time information about cellular morphology and margin involvement. These help operating surgeons understand the nature and extent of disease […]
Intraoperative Consultation (IOC) with a Frozen Section: Initial Block
The intra-operative frozen section plays a crucial role in the management of surgical patients. Frozen Section (FS) provides quick gross or microscopic diagnoses that can guide the intra- or perioperative management of a patient. This procedure provides real-time information about the nature of the tumor, its margin involvement, tissue invasion, etc. This guides operating surgeons […]
Special Staining Procedure: Oil Red O
Oil Red O is a special staining histopathology procedure that helps to selectively stain lipid droplets orange-red and enhance their appearance under microscopic examination. This test is valuable in evaluating disorders with abnormal lipid accumulation in tissues, such as fatty liver disease, lipoma, and liposarcomas. This test provides detailed information about lipogenic tissues, enhancing the […]
Special Staining Procedure: Alcian Blue, ABPAS, Congo Red, EVG (Van Gieson and Verhoff’s), Giemsa, Hales Colloidal Iron, Masson Trichrome, Mucicarmine, PAS, PASDiastase, PMS (Jones), Perl’s, Reticulin, & Von Kossa
These special staining procedures are specialized histopathology staining techniques that color specific cellular components, targets, or pathogens. They help to differentially highlight mucin, amyloid deposits, connective tissue fibers, collagen, and minerals, aiding in the easy identification of fibrosis, tumors, and metabolic disorders. These tests provide detailed information beyond routine histological features and enhance the accuracy […]
Special Staining Procedure: AFB, Wade Fite, GMS, Gram, Warhin Starry, Oil Red O
Special staining procedures such as AFB (acid-fast bacilli), Wade Fite, GMS (Grocott’s Methenamine Silver), Gram, Warthin-Starry, and Oil Red O are specialized histopathology staining techniques that color specific cellular components, targets, or pathogens. They deferentially highlight bacteria, fungi, mycobacteria, parasites, or lipid deposits in tissue sections, provide detailed information beyond routine histological features, and enhance […]
Decalcification Procedure
Decalcification procedures are utilized for the histopathological examination of biopsied specimens, especially those comprising hard tissue. It is generally performed by immersing these hard tissues in different decalcification fluids with several properties.
Pathology Tissue Request: Surgical Level VI
Level VI examination intends to examine a surgical pathology specimen with established neoplastic disease processes and an extensive multi-level examination of related tissues, requiring higher expertise in decision-making towards tissue diagnosis.
