Antithrombin III Assay
Antithrombin III regulates blood clotting, acting as a natural anticoagulant protein. Measuring its concentration and activity is indicated to investigate abnormal blood coagulation to assess thrombosis risk. This test helps healthcare professionals diagnose and manage patients with recurrent thrombosis, thromboembolism, and hereditary or acquired clotting disorders. The test is an integral part of clotting assay […]
Sickle Cell Solubility Test
The sickle cell solubility test is used to diagnose sickle cell disorders based on hemoglobin (HbS) insolubility in a reducing medium. A test involves a blood sample mixed with a reducing agent, inducing the sickling of red blood cells. This is a rapid preliminary screening test. Positive sickle cell screening can be confirmed by Hb […]
Pre-Marital Hb Analysis
Pre-marital hemoglobin analysis guides informed decision-making about prospective health and potential hereditary risks among marital partners. Hb Electrophoresis is an advanced method that separates and quantifies different hemoglobin fractions, revealing abnormalities or variations in their structure and providing the precise nature and severity of hemoglobin variants such as thalassemia, sickle hemoglobinopathies, or genetic hematological disorders […]
Heparin Induced Thrombocytopenia
Heparin-Induced Thrombocytopenia is a reaction associated with a reduced platelet count secondary to the use of the anticoagulant heparin. It occurs due to a non-immune reaction or antibodies that activate platelets and their premature removal from circulation. This is assessed by an enzyme-linked immunoassay to detect HIT-associated antibodies. Management involves heparin stoppage, platelet monitoring, and […]
Hemoglobin H Inclusions
The hemoglobin H inclusions test is a hematological test to identify HbH inclusions within red blood cells. These are abnormal hemoglobin formations formed by the aggregation of three alpha-globin chains, as seen in alpha-thalassemia. Their detection involves studying stained blood smears under a microscope. The presence of HbH inclusions aids in the diagnosis and management […]
Glucose-6-PD Qualitative
Glucose-6-Phosphate Dehydrogenase Qualitative refers to the qualitative assessment of the enzymatic activity of glucose-6-phosphate dehydrogenase, involved in the pentose phosphate pathway (PPP), which protects RBC from oxidative damage. G6PD deficiency is an inherited condition leading to hemolytic anemia. The test helps identify individuals with reduced or absent G6PD activity in susceptible individuals to avoid potentially […]
Cell Count with Differential Body Fluid
Cell count with Differential count in body fluids generally refers to assessing the cellular number, composition, and differential typing of cells in various body fluids, such as synovial fluid, pleural fluid, pericardial fluid, Bronco lavage fluid or peritoneal fluid. This study aids in diagnosing acute and chronic infections, inflammatory reactions, tumors, and cell deposits.
Cell Count with Differential CSF
Cerebrospinal fluid (CSF) cell count with differential is done to analyze the cellular components, number, and types of cells distributed in the CSF to obtain diagnostic information about various neurological conditions such as meningitis, encephalitis, and tumors. The total number of CSF cells counted on the stained slide is studied. An elevated count with differential […]
Platelet function screen
Platelets play a crucial role in hemostasis by adhering to the site of injury and undergoing aggregation to form a stable primary hemostatic plug. Platelet function screening tests assess the ability of platelets to form a primary plug through a series of whole-blood impedance aggregometry and platelet function analyzers combining bleeding time, platelet count, and […]
LMW Heparin Level
Low-Molecular-Weight Heparin (LMWH) is a type of anticoagulant medication similar to unfractionated heparin that works by enhancing antithrombin III activity. LMWH is clinically indicated for preventing and treating venous thromboembolism, deep vein thrombosis, coronary syndromes, and pulmonary embolism. Monitoring helps to maintain optimal LMWH levels for preventing, treating thromboembolic events and surgical prophylaxis. References: […]
