vWF Antigen
Von Willebrand Factor (vWF) is a glycoprotein that mediates adhesion of platelets to the site of vascular injury, protecting Factor VIII from degradation in the bloodstream and promoting platelet aggregation. Measuring vWF antigen levels is indicated to diagnose bleeding disorder and von Willebrand disease. Abnormal vWF levels can lead to bleeding tendencies. Testing helps in […]
Rivaroxaban, Anti Xa
Rivaroxaban is an oral anticoagulant that directly inhibits factor Xa, preventing the conversion of prothrombin to thrombin, the final step in the clotting process, preventing the formation of thrombin and blood clot formation. Anti-Xa assays for rivaroxaban are used to monitor anticoagulant therapy, optimize dosing, ensure therapeutic efficacy, and ensure effective prevention of thrombosis and […]
Reptilase Test
Reptilase, a specialized enzyme derived from snake venom, acts on fibrinogen, and converts it into fibrin, similar to the final steps of coagulation with natural thrombin. Heparin has no effect on its activity, unlike thrombin. The test is recommended when traditional clotting tests are affected by heparin, providing information on clotting ability independent of thrombin […]
Fondaparinux, Anti Xa
Fondaparinux is an oral anticoagulant inhibiting factor Xa, a critical protein in the blood coagulation cascade that causes the conversion of prothrombin to thrombin. Anti-Xa assays are used to monitor the levels of drugs like fondaparinux. This assay is used to monitor anticoagulant therapy, ensure therapeutic levels, and minimize bleeding risks in cases of deep […]
Fibrinogen Level
Fibrinogen is a key protein converted to fibrin during the final stages of the coagulation cascade. A fibrinogen assay is indicated to assess the adequacy of fibrinogen in the blood and helps to monitor suspected clotting disorders, liver disease, disseminated intravascular coagulation, inflammation, or certain cancers, or monitoring during certain therapies as abnormal fibrinogen levels […]
Cerebrospinal fluid (CSF) Oncology
Cerebrospinal fluid (CSF) cell count with differential is done to analyze the cellular components, number, and types of cells distributed in the CSF to obtain diagnostic information about various neurological conditions such as meningitis, encephalitis, and tumors. The total number of CSF cells counted on the stained slide is studied. An elevated count with differential […]
Coagulation Panel
The Coagulation Panel test measures activated partial thromboplastin time (aPTT), prothrombin time (PT), Fibrinogen and D-Dimer. These parameters assess various aspects of the blood’s ability to clot. It is commonly used to evaluate the function of the coagulation system and to diagnose or monitor bleeding disorders such as hemophilia or clotting disorders such as vitamin […]
Anti-Xa LMWH Test
The anti-Xa low molecular weight heparin (LMWH) assay is intended to quantify the plasma levels of LMWH during the treatment of thromboembolic accidents. Monitoring Anti-Xa LMWH helps healthcare providers optimize the dose of LMWH and ensure effective anticoagulation therapy in patients with high-risk trauma and burns. References: Gremillet M, Talon L, Lebreton A, Sinegre T. […]
Anti-Xa Heparin Test
Anti Xa Heparin test measures the functional level of heparins in plasma and helps to monitor anticoagulation therapy, especially in patients receiving unfractionated heparin. It helps healthcare professionals optimize the dosage and ensure effective anticoagulation therapy tailored to the specific needs of these patients. References: Gremillet M, Talon L, Lebreton A, Sinegre T. Monitoring heparin […]