Porphobilinogen Qualitative Urine
The urinary qualitative porphobilinogen test detects the presence of the pyrrole derivative Porphobilinogen (PBG), essential in heme synthesis. Elevated PBG levels are associated porphobilinogen deaminase enzyme deficiencies. Clinically, symptoms include dysautonomia, neuropathy, psychiatric manifestations, and severe abdominal pain episodes. This screening test used as swift diagnosis in acute intermittent porphyria, variegate porphyria, or hereditary coproporphyria.
PM Scl Antibodies
PM Scl Antibodies are immunological assays aiming to detect antibodies directed against the PMSCL protein, commonly found in the cell nucleus, a common association in autoimmune diseases. These antibodies are associated with a rare autoimmune disease known as polymyositis-scleroderma overlap syndrome or systemic sclerosis (scleroderma). This test helps in evaluating patients with clinical suspicion of […]
Platelet Antibody
The Platelet Antibody test identifies platelet antibodies, aiding in diagnosing thrombocytopenia linked with autoimmune disorders and platelet transfusion compatibility concerns. Platelet autoantibodies form when individuals develop sensitivities to platelet antigens in transfused blood, leading to the destruction of donor and recipient platelets. This test evaluates conditions like drug-induced immunologic thrombocytopenia, idiopathic thrombocytopenic purpura, and posttransfusion […]
Plasminogen
Plasminogen is a glycoprotein formed in the liver and circulates in the blood. Plasminogen is the precursor of plasmin, which lyses fibrin clots to fibrin degradation products. Plasminogen assay is employed by healthcare professionals for Pseudomembranous disease (e.g., ligneous conjunctivitis) as well as Idiopathic thromboembolic disease (if other causes of thrombophilia are eliminated).
Phencyclidine Screen Urine
The Phencyclidine (PCP) Urine Screen test detects the presence of the hallucinogenic substance Phencyclidine, a dissociative anesthetic that can be ingested intentionally or unintentionally. This substance exhibits a range of physical and behavioral effects and poses a significant risk of abuse and dependency. This test identifies acute toxicity resulting from drug abuse.
Pancreatic Islet Cell Ab
The Pancreatic Islet Cell Antibody test identifies islet antibodies associated with pancreatic autoimmunity in type 1 diabetes (T1D) which are crucial indicators of the autoimmune response and monitored for prognosis in individuals with T1D. This test identifies risk before the onset of T1D and explores the natural history of T1D onset for appropriate management.
Ovarian Antibodies
The Ovarian Antibodies test identifies the presence of antibodies that can lead to implantation failures in suspected cases of ovarian autoimmunity during in vitro fertilization. Healthcare professionals employ this test to diagnose premature ovarian failure, distinguish it from other causes of failure, and guide the restoration of ovarian function through appropriate immune modulation therapy.
Osteocalcin
The Osteocalcin test measures the levels of osteocalcin, a vitamin K-dependent protein produced by osteoblasts. This test functions as a noninvasive and specific marker of bone metabolism. Healthcare professionals utilize this test to identify individuals at risk of developing osteoporosis, monitor bone metabolism during and after menopause, and assess the response to antiresorptive therapy.
Oligoclonal Bands CSF
The Oligoclonal Bands (OCBs) in the cerebrospinal fluid (CSF) test identifies the central humoral response. CSF-restricted OCBs are indicative of multiple sclerosis (MS) its presence is also observed in other central nervous system disorders and neurodegenerative conditions. Healthcare professionals utilize this test to identify conditions such as systemic infections, autoimmune diseases, sarcoidosis, MS, or neoplasia.
Ntx-N Telopeptide Urine
Ntx-N Terminal Telopeptide Urine is a marker test to assess the extent of bone resorption, providing insights into bone metabolism and bone mineral matrix turnover. The test is indicated in evaluating bone strength in conditions such as osteoporosis and Paget’s disease. Elevated levels of NTx show increased bone resorption, suggesting accelerated bone turnover. The test […]
